Gen 12:1-5
GOD told Abram: "Leave your country, your family, and your father's home for a land that I will show you. 2 I'll make you a great nation and bless you. I'll make you famous; you'll be a blessing. 3 I'll bless those who bless you; those who curse you I'll curse. All the families of the Earth will be blessed through you."
4 So Abram left just as GOD said, and Lot left with him. Abram was seventy-five years old when he left Haran. 5 Abram took his wife Sarai and his nephew Lot with him, along with all the possessions and people they had gotten in Haran, and set out for the land of Canaan and arrived safe and sound.

This is what having faith means: he left his homeland with his barren wife.